Heritability of Obesity in Northeastern Mexico: A Study Based on Dyad (Mother-Child) Body Mass Index
Keywords:
Heritability, Obesity, Homogeneity, MéxicoAbstract
The aim of this quantitative genetic study was to estimate heritability (h2) of BMI in 2840 mother-child pairs to know if h2 values differ among five states of northeastern Mexico. The total h2 found among states was 51.6% and no significant differences were found among them (X2 = 5.24, p = 0.26). In conclusion, from a genetic epidemiology point of view, genome wide scan association studies can be carried out to find candidate genes in any of these Mexican populations not only for obesity (OB), but also other multifactorial diseases.
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